TOWARDS THE SYNTHESIS OF HIV-PROTEASE INHIBITORS - SYNTHESIS OF OPTICALLY PURE 3-CARBOXYL-DECAHYDROISOQUINOLINES

被引：32

作者：

HOUPIS, IN

MOLINA, A

REAMER, RA

LYNCH, JE

VOLANTE, RP

REIDER, PJ

机构：

[1] Merck Research Laboratories Department of Research, Rahway, NJ 07065, P.O. Box 2000

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(00)77633-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of optically pure decahydroisoquinoline 1, a component of HIV-protease inhibitors, was accomplished in 30-33% overall yield from the readily available optically pure monoacid 4.

引用

页码：2593 / 2596

页数：4

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