DEVELOPMENT OF A NONINVASIVE MONITORING INSTRUMENT FOR SERUM INDOCYANINE GREEN-DYE CONCENTRATION

被引：10

作者：

KANDA, M

NIWA, S

机构：

[1] Department of Biomedical Research and Development, Sumitomo Electric Industries Ltd., Konohana-ku, Osaka, 554

来源：

APPLIED OPTICS | 1992年 / 31卷 / 31期

关键词：

ICG; NONINVASIVE; MONITORING;

D O I：

10.1364/AO.31.006668

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A noninvasive instrument to monitor serum Indocyanine Green (ICG) dye removal by the liver, which uses a new analytical method and an optical sensor, has been developed. The principal elements of the optical sensor are two light-emitting diodes at 810- and 940-nm wavelengths and a photodiode to detect light transmittance through the fingertip. A new analytical calibration method to compensate for the effect of blood volume variations has been developed. Thereby, only ICG concentration could be extracted. In addition, through clinical evaluation of hepatic disease patients, the correlation between serum ICG disappearance rates by this method and the conventional blood sampling method has been confirmed as evidence of its usefulness.

引用

页码：6668 / 6675

页数：8

共 15 条

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ANDERSEN MN, 1970, ARCH SURG-CHICAGO, V100, P541

[2] ESTIMATION OF CARDIAC OUTPUT BY THE DYE DILUTION METHOD WITH AN EAR OXIMETER [J].