A RECIPROCAL WHOLE-ARM TRANSLOCATION, RCP(1-6)(1P6P-1Q6Q) IN A BOAR, LOCALIZATION OF THE BREAKPOINTS, AND REASSIGNMENT OF THE GENES FOR GLUCOSE PHOSPHATE ISOMERASE (GPI) AND CALCIUM RELEASE CHANNEL (CRC)

被引：13

作者：

YANG, H ^{[1
]}

JUNG, HR ^{[1
]}

SOLINASTOLDO, S ^{[1
]}

LANG, E ^{[1
]}

BOLT, R ^{[1
]}

FRIES, R ^{[1
]}

STRANZINGER, G ^{[1
]}

机构：

[1] SWISS FED INST TECHNOL, DEPT ANIM SCI, TANNENSTR 1, CH-8092 ZURICH, SWITZERLAND

来源：

CYTOGENETICS AND CELL GENETICS | 1992年 / 61卷 / 01期

关键词：

D O I：

10.1159/000133371

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A reciprocal whole-arm translocation between chromosomes 1 and 6 in a Swiss Large White boar with reduced fertility was identified by the use of different staining techniques in mitotic metaphase cells, synaptonemal complex analyses, and meiotic chromosome preparations. The karyotype of this boar was demonstrated to be 38,XY,rcp(1;6)(1 p6p; 1 q6q). To further localize the breakpoints more precisely and determine the precise gene locations. several in situ hybridization experiments were performed with a chromosome 1 centromere-specific probe and two other gene probes. The breakage and reunion points of both chromosomes were located in the centromeric regions. The genes for glucose phosphate isomerase and calcium release channel were mapped to 6cen --> q12.

引用

页码：67 / 74

页数：8

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