IDENTIFICATION OF AROMATIC KETONES IN CIGARETTE SMOKE CONDENSATE

Because of the complexity of cigarette smoke, extensive fractionation was necessary to isolate and identify minor components. The separation techniques involved solvent partition, column, paper, and gas chromatography. The gas chromatographic system allowed the collection of smoke constituents for subsequent analysis by ultraviolet and infrared spectroscopy and mass spectrometry. From the study of one subtraction which represents 0.08% of the original weight of the condensate, fluoren-9-one, the four methylfluoren-9-ones and seven other alkylated fluoren-9-ones were identified. © 1969, American Chemical Society. All rights reserved.