APPLICATION OF ROBUST NONLINEAR-REGRESSION METHODS FOR FITTING HYPERBOLIC SCATCHARD PLOTS

被引：15

作者：

WAHRENDORF, J

机构：

[1] Institute of Documentation, Information and Statistics, German Cancer Research Center, Heidelberg

来源：

INTERNATIONAL JOURNAL OF BIO-MEDICAL COMPUTING | 1979年 / 10卷 / 01期

关键词：

D O I：

10.1016/0020-7101(79)90043-6

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

The Scatchard plot is an essential tool for the estimation of binding parameters in biochemistry. In certain situations the fitting of a hyperbolic line is required in this context. It is proposed to solve this non-linear regression problem by robust methods. A method according to Huber and Dutter (1974) is outlined and its good applicability is demonstrated. © 1979.

引用

页码：75 / 87

页数：13

共 7 条

[1]

BICKEL PJ, 1976, SCAND J STAT, V3, P145

[2] EVALUATION OF FITTING METHODS FOR SUM OF 2 HYPERBOLAS - APPLICATION TO UPTAKE STUDIES [J].