CONFORMATIONAL STUDIES OF 2-METHYL-3-PHENYLPROPIONIC ACID, 2-PHENYLBUTYRIC ACID AND THEIR METHYL-ESTERS BY NMR-SPECTROSCOPY

被引：12

作者：

SPASSOV, SL

STEFANOVA, R

机构：

[1] Institute of Organic Chemistry, Bulgarian Academy of Sciences

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1979年 / 53卷 / 02期

关键词：

D O I：

10.1016/0022-2860(79)80344-0

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The conformational distribution of PhCH2CH(CH3)COOR and CH3CH2CH(Ph)COOR (R = H, CH3) has been studied by NMR spectroscopy. In the former case the conformer with the phenyl and carboxyl (or methoxycarbonyl) groups in the anti position relative to each other is favoured. For 2-phenylbutyric acid and its ester the forms with the methyl group gauche to phenyl or COOR are almost equally represented. The validity of the additive gauche-interaction scheme for prediction of conformational distribution in substituted ethanes is also discussed. © 1979.

引用

页码：219 / 224

页数：6

共 11 条

[1] ROTATIONAL-ISOMERISM .21. CONFORMATION OF 2-AMINO-3-FLUOROPROPANOIC ACID (2-AFP) AND 2-FLUORO-3-AMINOPROPANOIC ACID (3-AFP) AS ZWITTERION, CATION AND ANION, AN NMR AND MO STUDY [J].