RESTORATION OF THE DEFECTIVE NATURAL DEFENSE OF BEIGE MICE AGAINST TISSUE-MIGRATING LARVAE OF STRONGYLOIDES-RATTI BY TRANSFER WITH NORMAL PERITONEAL-CELLS

被引：8

作者：

ABE, T ^{[1
]}

YOSHIMURA, K ^{[1
]}

NAWA, Y ^{[1
]}

机构：

[1] MIYAZAKI MED COLL,DEPT PARASITOL,MIYAZAKI 88916,JAPAN

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1992年 / 22卷 / 04期

关键词：

BEIGE MICE; STRONGYLOIDES-RATTI; PERITONEAL CELLS; CELL TRANSFER;

D O I：

10.1016/0020-7519(92)90159-I

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The effects of cell transfer on the defective natural defences of beige (bg(j)/bg(j)) mice against Strongyloides ratti were studied by assessing recovery of tissue-migrating larvae from head and lung. Transfer of peritoneal resident cells from normal bg(j)/+ mice restored the defective natural defence of beige mice. The non-adherent population of normal peritoneal cells did not have the restorative capacity. Macrophages may be important to the natural defence against S. ratti.

引用

收藏

页码：545 / 547

页数：3

相关论文

共 10 条

[1] STRONGYLOIDES-RATTI - INCREASE IN SUSCEPTIBILITY TO INFECTION FOLLOWING BLOCKADE OF THE MONONUCLEAR PHAGOCYTE SYSTEM IN FEMALE MICE [J].

ABE, T ;

KIYOTA, M ;

NAWA, Y .

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 1985, 63 (DEC) :651-653

[2] DEFECTIVE GRANULOCYTE CHEMOTAXIS IN CHEDIAK-HIGASHI SYNDROME [J].

CLARK, RA ;

KIMBALL, HR .

JOURNAL OF CLINICAL INVESTIGATION, 1971, 50 (12) :2645-+

[3] STRONGYLOIDES-RATTI - SUSCEPTIBILITY TO INFECTION AND RESISTANCE TO RE-INFECTION IN INBRED STRAINS OF MICE AS ASSESSED BY EXCRETION OF LARVAE [J].

DAWKINS, HJS ;

GROVE, DI ;

DUNSMORE, JD ;

MITCHELL, GF .

INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1980, 10 (02) :125-129

[4]

GALLIN JI, 1975, BLOOD, V45, P863

[5] DESTRUCTION OF TRYPANOSOMA-CRUZI BY NATURAL-KILLER CELLS [J].

HATCHER, FM ;

KUHN, RE .

SCIENCE, 1982, 218 (4569) :295-296

[6] EFFECT OF ANDROGEN ON THE EXPRESSION OF THE SEX DIFFERENCE IN SUSCEPTIBILITY TO INFECTION WITH STRONGYLOIDES-RATTI IN C57BL/6 MICE [J].

KIYOTA, M ;

KORENAGA, M ;

NAWA, Y ;

KOTANI, M .

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 1984, 62 (OCT) :607-618

[7]

KORENAGA M, 1991, IMMUNOLOGY, V72, P502

[8] IMPAIRED NATURAL DEFENSE OF BEIGE (CHEDIAK-HIGASHI-SYNDROME) MICE AGAINST TISSUE-MIGRATING LARVAE OF STRONGYLOIDES-RATTI AND ITS RECONSTITUTION BY BONE-MARROW CELLS [J].

NAWA, Y ;

ABE, T ;

IMAI, J ;

MARUYAMA, H .

PARASITE IMMUNOLOGY, 1988, 10 (02) :117-126

[9] BEIGE MUTATION IN THE MOUSE SELECTIVELY IMPAIRS NATURAL KILLER CELL-FUNCTION [J].

RODER, J ;

DUWE, A .

NATURE, 1979, 278 (5703) :451-453

[10] SPECIFIC PROTEASE DEFICIENCY IN POLYMORPHONUCLEAR LEUKOCYTES OF CHEDIAK-HIGASHI-SYNDROME AND BEIGE MICE [J].

VASSALLI, JD ;

GRANELLIPIPERNO, A ;

GRISCELLI, C ;

REICH, E .

JOURNAL OF EXPERIMENTAL MEDICINE, 1978, 147 (04) :1285-1290