AN ENANTIOSELECTIVE SYNTHESIS OF (6R)-LACTACYSTIN

被引：43

作者：

COREY, EJ

CHOI, SY

机构：

[1] Department of Chemistry, Harvard University, Cambridge

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)61573-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first enantiospecific, stereocontrolled total synthesis of (6R)-lactacystin, a potential neurotrophic agent, is described.

引用

收藏

页码：6969 / 6972

页数：4

相关论文

共 8 条

[1] KEEPING TRACK OF NEUROTROPHIN RECEPTORS
BOTHWELL, M
[J]. CELL, 1991, 65 (06) : 915 - 918
[2] TOTAL SYNTHESIS OF LACTACYSTIN
COREY, EJ
REICHARD, GA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (26) : 10677 - 10678
[3] COREY EJ, 1992, TETRAHEDRON LETT, V33, P6735
[4] THE NERVE GROWTH-FACTOR 35 YEARS LATER
LEVIMONTALCINI, R
[J]. SCIENCE, 1987, 237 (4819) : 1154 - 1162
[5] NEW-PROTEIN FOLD REVEALED BY A 2.3-A RESOLUTION CRYSTAL-STRUCTURE OF NERVE GROWTH-FACTOR
MCDONALD, NQ
LAPATTO, R
MURRAYRUST, J
GUNNING, J
WLODAWER, A
BLUNDELL, TL
[J]. NATURE, 1991, 354 (6352) : 411 - 414
[6] STRUCTURE OF LACTACYSTIN, A NEW MICROBIAL METABOLITE WHICH INDUCES DIFFERENTIATION OF NEUROBLASTOMA-CELLS
OMURA, S
MATSUZAKI, K
FUJIMOTO, T
KOSUGE, K
FURUYA, T
FUJITA, S
NAKAGAWA, A
[J]. JOURNAL OF ANTIBIOTICS, 1991, 44 (01) : 117 - 118
[7] LACTACYSTIN, A NOVEL MICROBIAL METABOLITE, INDUCES NEURITOGENESIS OF NEUROBLASTOMA-CELLS
OMURA, S
FUJIMOTO, T
OTOGURO, K
MATSUZAKI, K
MORIGUCHI, R
TANAKA, H
SASAKI, Y
[J]. JOURNAL OF ANTIBIOTICS, 1991, 44 (01) : 113 - 116
[8] Rosenberg S., 1992, ANNU REP MED CHEM, V27, P41