INFLUENCE OF THE HEPATIC DRUG-METABOLIZING ENZYME-INDUCER PHENOBARBITONE ON CYCLOSPORINE NEPHROTOXICITY AND HEPATOTOXICITY IN RENAL-ALLOGRAFTED RATS

被引：13

作者：

DUNCAN, JI

HEYS, SD

THOMSON, AW

SIMPSON, JG

WHITING, PH

机构：

[1] UNIV ABERDEEN,DEPT PATHOL,ABERDEEN AB9 2ZD,SCOTLAND

[2] UNIV ABERDEEN,DEPT SURG,ABERDEEN AB9 2ZD,SCOTLAND

[3] UNIV ABERDEEN,DEPT CHEM PATHOL,ABERDEEN AB9 2ZD,SCOTLAND

来源：

TRANSPLANTATION | 1988年 / 45卷 / 04期

关键词：

D O I：

10.1097/00007890-198804000-00005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：693 / 697

页数：5

共 20 条

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[2] TOXICITY OF THE IMMUNE SUPPRESSANT CYCLOSPORIN-A IN THE RAT [J].

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[3] SERUM CYCLOSPORIN LEVELS, HEPATIC DRUG-METABOLISM AND RENAL TUBULOTOXICITY [J].

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WHITING, PH ;

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MACINTYRE, F ;

THOMSON, AW ;

SIMPSON, JG .

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[4] AMELIORATION OF CYCLOSPORIN-INDUCED NEPHROTOXICITY IN RATS BY INDUCTION OF HEPATIC DRUG-METABOLISM [J].

CUNNINGHAM, C ;

BURKE, MD ;

WHEATLEY, DN ;

THOMSON, AW ;

SIMPSON, JG ;

WHITING, PH .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (04) :573-578

[5]

DUNCAN J, 1986, CLIN NEPHROL S1, V25, P514

[6]

DUNCAN JI, 1986, TRANSPLANT P, V18, P645

[7]

Fabre J, 1971, Aust N Z J Surg, V41, P69

[8] INHIBITED EFFICIENCY OF KIDNEY MITOCHONDRIA ISOLATED FROM RATS TREATED WITH CYCLOSPORINE-A [J].

JUNG, K ;

REINHOLDT, C ;

SCHOLZ, D .

NEPHRON, 1987, 45 (01) :43-45

[9]

KAHAN BD, 1985, TRANSPLANT P S1, V17

[10]

KLINTMALM GBG, 1981, LANCET, V1, P470

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