MOUSE ANTI-MORPHINE CONSTIPATION TEST - SIMPLE LABORATORY TEST OF THE GASTRO-INTESTINAL SIDE-EFFECT POTENTIAL OF ORALLY-ADMINISTERED PROSTAGLANDIN ANALOGS

被引:6
作者
CHRISTMAS, AJ
机构
[1] Pharmacological Research Laboratories, May and Baker Ltd., Dagenham
关键词
D O I
10.1016/0090-6980(79)90114-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A test is described which is simple, reliable and highly sensitive to the diarrhoea-inducing properties of orally administered prostaglandin analogues in mice. Comparison with human data shows similar orders of relative potency. © 1979.
引用
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页码:279 / 284
页数:6
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