A PRELIMINARY-STUDY OF THE BIOAVAILABILITY OF IRON-GLYCINE AND ZINC-GLYCINE CHELATES

被引：10

作者：

FAIRWEATHERTAIT, SJ

FOX, TE

WHARF, SG

GHANI, NA

机构：

[1] AFRC Institute of Food Research, Norwich Laboratory, Colney, Norwich, NR4 7UA, Norwich Research Park

来源：

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT | 1992年 / 9卷 / 01期

关键词：

IRON BIOAVAILABILITY; ZINC BIOAVAILABILITY; METAL GLYCINE CHELATES;

D O I：

10.1080/02652039209374049

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Groups of rats were fed diets containing marginal levels of Fe and Zn as glycine chelates (tradename 'Chelazome', Albion Laboratories, Verona, New Jersey, USA), or the same level of mineral as ferrous sulphate or zinc carbonate. The Fe diets were fed to weanling rats for 4 weeks and the Zn diets to young adult rats for 5 weeks. Blood Hb concentrations were significantly higher in the group fed Fe-chelazome than ferrous sulphate, 149 and 128 g/l respectively (P < 0.001), but PCV and liver Fe concentrations were similar between the two groups. No difference in plasma Zn, pancreas, testes or femur Zn concentrations were observed between the two Zn groups, indicating that Zn-chelazome has no advantage over zinc carbonate. The results of this preliminary study indicate that Fe-chelazome has a higher bioavailability than ferrous sulphate and merits further study.

引用

页码：97 / 101

页数：5

共 12 条

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