A CONCISE SYNTHESIS OF TAIWANIN-E USING A MICHAEL INITIATED RING-CLOSURE PROTOCOL

被引：28

作者：

HARROWVEN, DC

机构：

[1] Department of Chemistry, The University, Nottingham

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 30期

关键词：

TAIWANIN-E; PODOPHYLLUM LIGNANS; MICHAEL INITIATED RING CLOSURE; ARYLNAPHTHALENE LIGNANS; PODOPHYLLOTOXIN;

D O I：

10.1016/S0040-4039(00)79781-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rapid entry towards the Podophyllum lignans is described exemplified by a concise regioselective total synthesis of taiwanin E (2). The synthesis features a Michael initiated ring closure sequence to access the key lignan intermediate (11) from the ketodithiolane (10) and the furanone (4).

引用

页码：3735 / 3738

页数：4

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