CRYSTAL AND MOLECULAR STRUCTURE OF A THYMINE-THYMINE ADDUCT

被引：40

作者：

KARLE, IL

WANG, SY

VARGHESE, AJ

机构：

[1] Naval Research Laboratory, Laboratory for the Structure of Matter, Washington

[2] Johns Hopkins University, School of Hygiene and Public Health, Baltimore

来源：

SCIENCE | 1969年 / 164卷 / 3876期

关键词：

D O I：

10.1126/science.164.3876.183

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Thymine-thymine adduct is a product isolated from thymine irradiated with ultraviolet light in frozen aqueous solution. This compound is presumably formed through the rearrangement of an initial photoproduct. Single crystal x-ray diffraction analysis has confirmed the molecular formula of the adduct, 5-hydroxy6-4′-(5′-methylpyrimid-2′-one)-dihydrothymine, except for the possibility of a hydrogen atom on the 3 ′nitrogren rather than the 1 ′ nitrogen, and has established the stereoconfiguration of the molecule.

引用

页码：183 / &

共 19 条

[1]

ADMAN ET, IN PRESS

[2] ISOLATION AND IDENTIFICATION OF THE IRRADIATION PRODUCT OF THYMINE [J].