THE BEX LOCUS IN ENCAPSULATED HAEMOPHILUS-INFLUENZAE - A CHROMOSOMAL REGION INVOLVED IN CAPSULE POLYSACCHARIDE EXPORT

被引：134

作者：

KROLL, JS ^{[1
]}

LOYNDS, B ^{[1
]}

BROPHY, LN ^{[1
]}

MOXON, ER ^{[1
]}

机构：

[1] UNIV OXFORD,JOHN RADCLIFFE HOSP,DEPT PAEDIAT,OXFORD OX3 9DU,ENGLAND

来源：

MOLECULAR MICROBIOLOGY | 1990年 / 4卷 / 11期

关键词：

D O I：

10.1111/j.1365-2958.1990.tb02034.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nucleotide sequence of a 5.1 kb region in the Haemophiius influenzae type b capsulation locus has been determined and found to contain four open reading frames: bexD, bexC, bexB, and bexA. Comparison of the deduced products of bexC, bexB, and bexA to known proteins, and TnphoA mutagenesis, suggests that they form components of an ATP‐driven polysaccharide export apparatus. Furthermore, close sequence similarity between BexA and BexB and products of the kpsT and kpsM genes at the Escherichia coli K5 capsulation locus (Smith et al., 1990 — accompanying paper) suggests that capsulation genes in these organisms may have a common ancestry. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：1853 / 1862

页数：10

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