IMMUNITY INDUCED IN RATS VACCINATED WITH TOXOID PREPARED FROM HEAT-LABILE TOXIN PRODUCED BY PASTEURELLA-MULTOCIDA SEROGROUP-D

被引：10

作者：

THURSTON, JR

RIMLER, RB

ACKERMANN, MR

CHEVILLE, NF

SACKS, JM

机构：

[1] United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Ames

来源：

VETERINARY MICROBIOLOGY | 1991年 / 27卷 / 02期

关键词：

D O I：

10.1016/0378-1135(91)90008-4

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Rats were vaccinated with a toxoid (D-toxoid) prepared from purified heat-labile toxin (D-toxin) produced by Pasteurella multocida serogroup D. Vaccination of rats with D-toxoid prevented death and other effects of D-toxin (hepatic necrosis, development of elevated leukocyte counts, lymphopenia, neutrophilia, and elevated complement titers) that occurred in phosphate buffered saline (PBS)-vaccinated control rats.

引用

页码：169 / 174

页数：6

共 14 条

[1]

CHANTER N, 1989, PASTEURELLA PASTEURE

[2] A TOXIN FROM PASTEURELLA-MULTOCIDA TYPE-D CAUSES ACUTE HEPATIC-NECROSIS IN PIGS [J].

CHEVILLE, NF ;

RIMLER, RB ;

THURSTON, JR .

VETERINARY PATHOLOGY, 1988, 25 (06) :518-520

[3] A PROTEIN TOXIN FROM PASTEURELLA-MULTOCIDA TYPE-D CAUSES ACUTE AND CHRONIC HEPATIC TOXICITY IN RATS [J].

CHEVILLE, NF ;

RIMLER, RB .

VETERINARY PATHOLOGY, 1989, 26 (02) :148-157

[4]

DOMINICK MA, 1986, AM J VET RES, V47, P1532

[5] TURBINATE OSTEOPOROSIS IN PIGS FOLLOWING INTRANASAL INOCULATION OF PURIFIED PASTEURELLA TOXIN - HISTOMORPHOMETRIC AND ULTRASTRUCTURAL STUDIES [J].

DOMINICK, MA ;

RIMLER, RB .

VETERINARY PATHOLOGY, 1988, 25 (01) :17-27

[6] CHARACTERIZATION OF THE DERMAL LESIONS INDUCED BY A PURIFIED PROTEIN FROM TOXIGENIC PASTEURELLA-MULTOCIDA [J].

ELLING, F ;

PEDERSEN, KB ;

HOGH, P ;

FOGED, NT .

APMIS, 1988, 96 (01) :50-55

[7]

ELLING F, 1986, 4TH JOINT M VET PATH

[8] QUANTITATION AND PURIFICATION OF THE PASTEURELLA-MULTOCIDA TOXIN BY USING MONOCLONAL-ANTIBODIES [J].

FOGED, NT .

INFECTION AND IMMUNITY, 1988, 56 (08) :1901-1906

[9] PROTECTION AGAINST PROGRESSIVE ATROPHIC RHINITIS BY VACCINATION WITH PASTEURELLA-MULTOCIDA TOXIN PURIFIED BY MONOCLONAL-ANTIBODIES [J].

FOGED, NT ;

NIELSEN, JP ;

JORSAL, SE .

VETERINARY RECORD, 1989, 125 (01) :7-11

[10]

Garvey JS, 1977, METHODS IMMUNOLOGY

← 1 2 →