DIFFERENCES IN THE AXON COMPOSITION OF NERVES SUPPLYING THE RAT KNEE-JOINT FOLLOWING INTRAARTICULAR INJECTION OF CAPSAICIN

被引：15

作者：

FERRELL, WR

LAM, FY

MONTGOMERY, I

机构：

[1] Institute of Physiology, University of Glasgow, Glasgow

来源：

NEUROSCIENCE LETTERS | 1992年 / 141卷 / 02期

关键词：

CAPSAICIN; UNMYELINATED NERVE; MYELINATED NERVE;

D O I：

10.1016/0304-3940(92)90908-P

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This study was used to examine the ultrastructure of articular nerves supplying the medial aspect of the rat knee joint following injection of capsaicin into the synovial cavity. One week after the intra-articular injection of 0.2 ml of 1% capsaicin solution there was significant reduction in the number of unmyelinated fibres. Two weeks post-injection this appeared to recover and by 4 weeks post-injection no further changes were observed. Myelinated fibres were unaffected by capsaicin injection. This procedure provides an effective means of producing short-term degeneration of unmyelinated fibres innervating the knee joint.

引用

页码：259 / 261

页数：3

共 11 条

[1] CAPSAICIN APPLIED TO PERIPHERAL-NERVE INHIBITS AXOPLASMIC-TRANSPORT OF SUBSTANCE-P AND SOMATOSTATIN [J].