WEAK BINDING OF ERYTHROMYCIN ANALOGS TO BACTERIAL-RIBOSOMES - A H-1-NMR STUDY

被引：14

作者：

BRENNAN, RJ

AWAN, A

BARBER, J

HUNT, E

KENNEDY, KL

SADEGHOLNEJAT, S

机构：

[1] UNIV MANCHESTER,DEPT PHARM,MANCHESTER M13 9PL,LANCS,ENGLAND

[2] SMITHKLINE BEECHAM PHARMACEUT,BETCHWORTH RH3 7AJ,SURREY,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 13期

关键词：

D O I：

10.1039/c39940001615

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Weak binding of a number of erythromycin analogues to bacterial ribosomes is monitored by H-1 NMR methods; transferred NOE data are shown to correlate with antibacterial activity.

引用

页码：1615 / 1617

页数：3

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