A MODEL FOR DISTRIBUTION AND TRANSPORT OF CO2 IN BODY AND VENTILATORY RESPONSE TO CO2

被引：24

作者：

MATTHEWS, CM

LASZLO, G

CAMPBELL, EJ

READ, DJC

机构：

[1] M.R.C. Cyclotron Unit, Royal Postgraduate Medical School, Hammersmith Hospital, W.12, England, Ducane Road, London

来源：

RESPIRATION PHYSIOLOGY | 1968年 / 6卷 / 01期

关键词：

Body compartments; CO[!sub]2[!/sub] stores; Model of CO[!sub]2[!/sub] distribution;

D O I：

10.1016/0034-5687(68)90018-2

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

A mathematical model has been constructed which simulates changes in ventilation, PCO2, bicarbonate and hydrogen ion concentrations in different body compartments during rebreathing, CO2 inhalation and hyperventilation. The model is based on equations for the balance of ions, Hendersonś equation, and Van Slyke's equation for buffering power applied to CO2, bicarbonate, and haemoglobin buffer in a system of body compartments. The system of compartments is based on the results obtained in experiments with 11C labelled CO2 described in the previous paper. The equations are simulated on a digital computer. The computer values match a number of experimental results and the model clarifies the relations between the various parameters involved. © 1968.

引用

页码：45 / +

页数：1

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