CHEMICAL SYNTHESIS, SEPARATION, AND IDENTIFICATION OF DIASTEREOISOMERS OF P1,P4-DITHIO-5',5'''-DIADENOSYL P1,P4-TETRAPHOSPHATE AND ITS P2,P3-METHYLENE ANALOGS

被引：12

作者：

BLACKBURN, GM

GUO, MJ

机构：

[1] Department of Chemistry, University of Sheffield, Sheffield

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(00)97625-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chemical synthesis, separation of diastereoisomers, and stereochemical characterisation of four P1,P4-dithiophosphate analogues of diadenosyl 5′,5‴-P1,P4-tetraphosphate are described. This provides direct access to β,γ-CHFbridged analogues of ATP with resolved stereochemistry at the CHF centre. © 1990.

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页码：4371 / 4374

页数：4

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