ELECTROCHEMICAL OXIDATION OF DERIVATIVES OF DIBENZODIAZEPIN, DIBENZOTHIAZEPIN AND DIBENZOXAZEPIN

被引：26

作者：

KAUFFMANN, JM ^{[1
]}

PATRIARCHE, GJ ^{[1
]}

CHRISTIAN, GD ^{[1
]}

机构：

[1] UNIV WASHINGTON,DEPT CHEM,SEATTLE,WA 98195

来源：

ANALYTICAL LETTERS PART B-CLINICAL AND BIOCHEMICAL ANALYSIS | 1979年 / 12卷 / 11期

关键词：

clothiapin loxapin; clozapin; Electrochemistry cyclic voltammetry nonaqueous solvents;

D O I：

10.1080/00032717908067911

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Clozapin exhibits two anodic waves at > 1 M H2SO4 but at lower acidities only the first two-electron wave remains.Cyclic voltammetry shows an ECE mechanism. Reversibility decreases at>10-4 M concentrations,due to formation of an adsorption film.In nonaqueous solvents two irreversible one-electron waves appear.Clothiapin and loxapin are more difficultly oxidized and can be measured in the presence of clozapin. © 1979, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：1217 / 1234

页数：18

共 11 条

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