ADVERSE EVENTS AND TREATMENT DISCONTINUATIONS IN FLUOXETINE CLINICAL-TRIALS

被引：48

作者：

PANDE, AC

SAYLER, ME

机构：

[1] Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, 46285, Lilly Corporate Center

来源：

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1993年 / 8卷 / 04期

关键词：

DRUG THERAPY; ADVERSE EVENTS; FLUOXETINE; TRICYCLIC ANTIDEPRESSANTS;

D O I：

10.1097/00004850-199300840-00010

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A re-analysis of the profile of adverse events observed in controlled clinical trials in summarized. The data confirm that the side-effects of fluoxetine therapy are different from those of the tricyclic antidepressants (TCAs), both in type and frequency. Moreover, the superior tolerability of fluoxetine compared with the TCAs is confirmed by the significantly lower rate of premature discontinuation in the fluoxetine-treated patients than in the TCA-treated patients.

引用

页码：267 / 269

页数：3

共 6 条

[1]

BEASLEY CM, 1990, PSYCHOPHARMACOL BULL, V26, P18

[2] METAANALYSIS IN CLINICAL-TRIALS [J].