Poly(A) and translation: development control

被引：69

作者：

Wormington, Michael ^{[1
]}

机构：

[1] Univ Virginia, Dept Biol, Charlottesville, VA 22903 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0955-0674(93)90075-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The stage-specific translational control of maternal mRNAs is determined by their differential polyadenylation and deadenylation. In the past year, a growing number of cis-acting elements that both positively and negatively regulate polyadenylation and deadenylation have been delineated. Considerable progress has been made on the biochemical characterization and regulation of trans-acting polyadenylation and deadenylation factors. This review summarizes these advances and their relevance to the roles of polyadenylation and deadenylation in translational control.

引用

页码：950 / 954

页数：5

共 35 条

[1]

ASTROM J, 1992, J BIOL CHEM, V267, P18154

[2] A MATERNAL TAIL OF POLY(A) - THE LONG AND THE SHORT OF IT [J].

BACHVAROVA, RF .

CELL, 1992, 69 (06) :895-897

[3] CHANGES IN RNA TITERS AND POLYADENYLATION DURING OOGENESIS AND OOCYTE MATURATION IN XENOPUS-LAEVIS [J].

DWORKIN, MB ;

DWORKINRASTL, E .

DEVELOPMENTAL BIOLOGY, 1985, 112 (02) :451-457

[4] POLY(A) ADDITION DURING MATURATION OF FROG OOCYTES - DISTINCT NUCLEAR AND CYTOPLASMIC ACTIVITIES AND REGULATION BY THE SEQUENCE UUUUUAU [J].

FOX, CA ;

SHEETS, MD ;

WICKENS, MP .

GENES & DEVELOPMENT, 1989, 3 (12B) :2151-2162

[5] POLYADENYLATION OF MATERNAL MESSENGER-RNA DURING OOCYTE MATURATION - POLY(A) ADDITION INVITRO REQUIRES A REGULATED RNA-BINDING ACTIVITY AND A POLY(A) POLYMERASE [J].

FOX, CA ;

SHEETS, MD ;

WAHLE, E ;

WICKENS, M .

EMBO JOURNAL, 1992, 11 (13) :5021-5032

[6] POLY(A) REMOVAL DURING OOCYTE MATURATION - A DEFAULT REACTION SELECTIVELY PREVENTED BY SPECIFIC SEQUENCES IN THE 3' UTR OF CERTAIN MATERNAL MESSENGER-RNAS [J].

FOX, CA ;

WICKENS, M .

GENES & DEVELOPMENT, 1990, 4 (12B) :2287-2298

[7] TRANSIENT TRANSLATIONAL SILENCING BY REVERSIBLE MESSENGER-RNA DEADENYLATION [J].

HUARTE, J ;

STUTZ, A ;

OCONNELL, ML ;

GUBLER, P ;

BELIN, D ;

DARROW, AL ;

STRICKLAND, S ;

VASSALLI, JD .

CELL, 1992, 69 (06) :1021-1030

[8] TRANSLATIONAL INACTIVATION OF RIBOSOMAL-PROTEIN MESSENGER-RNAS DURING XENOPUS OOCYTE MATURATION [J].

HYMAN, LE ;

WORMINGTON, WM .

GENES & DEVELOPMENT, 1988, 2 (05) :598-605

[9] DO THE POLY(A) TAIL AND 3' UNTRANSLATED REGION CONTROL MESSENGER-RNA TRANSLATION [J].

JACKSON, RJ ;

STANDART, N .

CELL, 1990, 62 (01) :15-24

[10] CYTOPLASMIC REGULATION OF MESSENGER-RNA FUNCTION - THE IMPORTANCE OF THE 3' UNTRANSLATED REGION [J].

JACKSON, RJ .

CELL, 1993, 74 (01) :9-14

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