AHAPTOGLOBINEMIA IN NORTHEASTERN BRAZIL

被引：6

作者：

AZEVEDO, E

KRIEGER, H

MORTON, NE

机构：

[1] Population Genetics Laboratory, University of Hawaii, Honolulu, HI

来源：

HUMAN HEREDITY | 1969年 / 19卷 / 06期

关键词：

D O I：

10.1159/000152275

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Haptoglobin level in this population is not significantly dependent on any factor except the Hp locus. Hp 1 gene dosage increases, and lip 2m markedly diminishes, the haptoglobin level. Ahaptoglobinemia (insufficient haptoglobin to permit electrophoretic typing of unconcentrated serum) is associated with abnormal hemoglobins, independently with low hematocrit, and especially with the Tip 2m gene. The observed frequency of ahaptoglobinemia in Brazilian Negroes, comparable to the prevalence in North American Negroes, may be due entirely to the Hp 2m allele, which appears to vary in its expression from Hp 2-1 to Hp 0. © 1969 S. Karger AG, Basel.

引用

页码：609 / &

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