ANALYSIS OF THE VENOM OF THE SYDNEY FUNNEL-WEB SPIDER, ATRAX-ROBUSTUS USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

被引:26
作者
DUFFIELD, PH [1 ]
DUFFIELD, AM [1 ]
CARROLL, PR [1 ]
MORGANS, D [1 ]
机构
[1] UNIV NEW S WALES,SCH PHYSIOL & PHARMACOL,KENSINGTON 2033,NEW S WALES,AUSTRALIA
来源
BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 03期
关键词
D O I
10.1002/bms.1200060305
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Thirteen compounds have been identified using gas chromatography mass spectrometry in the venom of the Sydney funnel‐web spider, Atrax robustus. The compounds were identified as their trimethylsilyl or pentafluoropropionate derivatives and were citric acid, lactic acid, phosphoric acid, glycerol, urea, glucose, γ‐aminobutyric acid, glycine, spermidine, spermidine, tyramine and octopamine. Female venom contained trace quantities of 5‐methyoxytryptamine which was not detected in male venom. Quantitative determination of tyramine and octopamine was achieved using chemical ionization (CH4) gas chromatography mass spectrometry and deuterated internal standards. Copyright © 1979 Heyden & Son Ltd
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页码:105 / 108
页数:4
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