TOTAL SYNTHESIS OF (-)-CEPHALOTAXINE

被引：112

作者：

ISONO, N

MORI, M

机构：

[1] Faculty of Pharmaceutical Sciences, Hokkaido University

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 01期

关键词：

D O I：

10.1021/jo00106a023

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Total synthesis of (-)-cephalotaxine was achieved from D-(+)-proline by a short sequence of steps. The key intermediate, 1-azaspiro[4.4]nonane, was prepared from vinyl iodide, using stannyl anion generated from Me(3)SiSnBu(3) and CsF, in good yield.

引用

页码：115 / 119

页数：5

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