ANTIGENIC HOMOLOGY AMONG CORONAVIRUSES RELATED TO TRANSMISSIBLE GASTROENTERITIS VIRUS

被引：129

作者：

SANCHEZ, CM

JIMENEZ, G

LAVIADA, MD

CORREA, I

SUNE, C

BULLIDO, MJ

GEBAUER, F

SMERDOU, C

CALLEBAUT, P

ESCRIBANO, JM

ENJUANES, L

机构：

[1] UNIV AUTONOMA MADRID,CSIC,CTR BIOL MOLEC,CANTO BLANCO,E-28049 MADRID,SPAIN

[2] INST NACL INVEST AGR,DEPT SANIDAD ANIM,E-28012 MADRID,SPAIN

[3] FAC DIERGENEESKUNDE GENT,VIROL LAB,B-9000 GHENT,BELGIUM

来源：

VIROLOGY | 1990年 / 174卷 / 02期

关键词：

D O I：

10.1016/0042-6822(90)90094-8

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The antigenic homology of 26 coronavirus isolates, of which 22 were antigenically related to transmissible gastroenteritis virus (TGEV), was determined with 42 monoclonal antibodies. Type, group, and interspecies specific epitopes were defined. Two group specific MAbs distinguished the enteric TGEV isolates from the respiratory variants. An antigenic subsite involved in neutralization was conserved in porcine, feline, and canine coronavirus. The classification of the human coronavirus 229E in a taxonomic cluster distinct from TGEV group is suggested. © 1990.

引用

页码：410 / 417

页数：8

共 48 条

[1]

AYNAUD JM, 1984, ANN RECH VET, V15, P347

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