BIOCATALYTIC RESOLUTIONS OF ALPHA-METHYLENE-BETA-HYDROXY ESTERS AND KETONES

被引:51
作者
BURGESS, K
JENNINGS, LD
机构
[1] Rice University, Department of Chemistry, Texas 77251, Box 1892, Houston
关键词
D O I
10.1021/jo00291a006
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
α-Methylene-β-hydroxy esters and ketones are resolved via lipase mediated irreversible acylations;1 experiments with a range of substrates have been used to identify factors that influence the enantioselection obtained and reaction times required. © 1990, American Chemical Society. All rights reserved.
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页码:1138 / 1139
页数:2
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