THE NEONATAL TESTOSTERONE SURGE - A COMPARATIVE-STUDY

被引：183

作者：

CORBIER, P ^{[1
]}

EDWARDS, DA ^{[1
]}

ROFFI, J ^{[1
]}

机构：

[1] EMORY UNIV,ATLANTA,GA 30322

来源：

ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE | 1992年 / 100卷 / 02期

关键词：

D O I：

10.3109/13813459209035274

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the rat an abrupt discharge of testicular testosterone in the newborn male figures prominently in the development of mechanisms controlling gonadotropin secretion, sexual behavior, and also promotes the functional differentiation of the accessory sex glands. In this study we detail the temporal characteristics of this surge in the rat, and we provide comparative data documenting a similar surge-like appearance of testosterone in neonatal male mice, recently foaled male horses, and newborn human infants. Although the physiological and behavioral significance of this phenomenon for species other than the rat remains to be determined, the apparently ubiquitous appearance of the neonatal testosterone surge suggests that it may be of special significance in the sexual differentiation of many mammalian species.

引用

页码：127 / 131

页数：5

共 20 条

[1] PRODUCTION OF ANOVULATORY, STERILE RATS BY SINGLE INJECTIONS OF TESTOSTERONE PROPIONATE [J].