A SHORT SYNTHESIS OF N-(A)-METHYLERVITSINE - REACTIVITY OF THE INTERMEDIATE 1,4-DIHYDROPYRIDINE TOWARDS ELECTROPHILES

被引：14

作者：

BENNASAR, ML ^{[1
]}

VIDAL, B ^{[1
]}

BOSCH, J ^{[1
]}

机构：

[1] UNIV BARCELONA,FAC PHARM,ORGAN CHEM LAB,E-08028 BARCELONA,SPAIN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 02期

关键词：

D O I：

10.1039/c39950000125

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A four-step synthesis of N-(a)-methylervitsine involving the nucleophilic addition of the enolate derived from acetylindole 2 to pyridinium salt 3, with subsequent C6H5SeBr-promoted cyclization of the resulting 1,4-dihydropyridine and further elaboration of the exocyclic 20E-ethylidene and 16-methylene substituents, is reported.

引用

页码：125 / 126

页数：2

共 14 条

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