A CONVENIENT PROCEDURE FOR THE SYNTHESIS OF ENYNE-ALLENES

被引:21
作者
WANG, KK
WANG, ZG
机构
[1] Department of Chemistry, West Virginia University, Morgantown
基金
美国国家科学基金会;
关键词
D O I
10.1016/S0040-4039(00)73171-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Bromoboration of 1-hexyne with BBr3 followed by treatment with 2-propanol produced alkenyl boronic ester 3. Subsequent Pd(0)-catalyzed cross-coupling with acetylenic zinc chlorides and iodination furnished enyne iodides 6, which were then converted to enyne-allenes 8 by a second Pd(0)-catalyzed reaction with allenic zinc chlorides.
引用
收藏
页码:1829 / 1832
页数:4
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