SYNTHESIS OF PHENYLALANINES REGIOSPECIFICALLY LABELED WITH DEUTERIUM IN THE AROMATIC RING

被引:13
作者
NISHIYAMA, K [1 ]
OBA, M [1 ]
UENO, R [1 ]
MORITA, A [1 ]
NAKAMURA, Y [1 ]
KAINOSHO, M [1 ]
机构
[1] TOKYO METROPOLITAN UNIV,DEPT CHEM,HACHIOJI,TOKYO 19203,JAPAN
关键词
H-2-LABELED L-PHENYLALANINES; H-2-LABELED L-TYROSINES; TYROSINE TETRAZOLYL ETHER; HYDROGENOLYSIS; CATALYTIC DEUTERATION;
D O I
10.1002/jlcr.2580340905
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Phenylalanines regiospecifically labelled with deuterium in the aromatic ring can be prepared through the hydrogenolysis of tyrosine tetrazolyl ethers using D-2 gas and a medium pressure catalytic hydrogenator.
引用
收藏
页码:831 / 837
页数:7
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