OXAZOLINE FORMATION VIA A PALLADIUM-CATALYZED CYCLIZATION - A DIRECT, STEREOSELECTIVE APPROACH TO CIS-5-AMINO-2-CYCLOPENTEN-1-OL DERIVATIVES

被引：25

作者：

HANSEL, JG ^{[1
]}

OHOGAN, S ^{[1
]}

LENSKY, S ^{[1
]}

RITTER, AR ^{[1
]}

MILLER, MJ ^{[1
]}

机构：

[1] UNIV NOTRE DAME,DEPT CHEM & BIOCHEM,NOTRE DAME,IN 46556

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 17期

关键词：

D O I：

10.1016/0040-4039(95)00465-O

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alanyl substituted 4-amino-2-cyclopenten-1-yl acetates were obtained optically pure in three steps from cyclopentadiene. The Pd-0 catalyzed cyclization of these allylic acetates was studied using protected and unprotected derivatives. A novel oxazoline synthesis was developed and its utility was demonstrated by the preparation of a cis-5-amino-2-cyclopenten-1-ol derivative.

引用

页码：2913 / 2916

页数：4

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