QUALITY-OF-LIFE QUESTIONNAIRES IN CANCER CLINICAL-TRIALS - IMPUTING MISSING VALUES

被引：30

作者：

MORRIS, J ^{[1
]}

COYLE, D ^{[1
]}

机构：

[1] UNIV YORK,CTR HLTH ECON,YORK YO1 5DD,N YORKSHIRE,ENGLAND

来源：

PSYCHO-ONCOLOGY | 1994年 / 3卷 / 03期

关键词：

D O I：

10.1002/pon.2960030308

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Quality of life is increasingly being used as a measure of outcome in comparative cancer clinical trials. Even when quality of life studies are well funded vis-a-vis data collection and processing, it is unlikely that data sets will be 100% complete, leading to problems at the data analysis stage. Missing data can arise as a consequence of whole assessments being missed due to death or other reasons, or as a result of single items being omitted from particular questionnaires. This paper addresses the latter category of missing data and examines the effects on subscale scores of imputing values for missing items from the Hospital Anxiety and Depression Scale and the psychological complaints subscale of the Rotterdam Symptom Checklist.

引用

页码：215 / 222

页数：8

共 11 条

[1]

AARONSON N, 1991, EFFECT CANCER QUALIT, P1985

[2] THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER QLQ-C30 - A QUALITY-OF-LIFE INSTRUMENT FOR USE IN INTERNATIONAL CLINICAL-TRIALS IN ONCOLOGY [J].

AARONSON, NK ;

AHMEDZAI, S ;

BERGMAN, B ;

BULLINGER, M ;

CULL, A ;

DUEZ, NJ ;

FILIBERTI, A ;

FLECHTNER, H ;

FLEISHMAN, SB ;

DEHAES, JCJM ;

KAASA, S ;

KLEE, M ;

OSOBA, D ;

RAZAVI, D ;

ROFE, PB ;

SCHRAUB, S ;

SNEEUW, K ;

SULLIVAN, M ;

TAKEDA, F .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (05) :365-376

[3] MEASURING PSYCHOLOGICAL AND PHYSICAL DISTRESS IN CANCER-PATIENTS - STRUCTURE AND APPLICATION OF THE ROTTERDAM-SYMPTOM-CHECKLIST [J].

DEHAES, JCJM ;

VANKNIPPENBERG, FCE ;

NEIJT, JP .

BRITISH JOURNAL OF CANCER, 1990, 62 (06) :1034-1038

[4]

Fayers P M, 1983, Stat Med, V2, P429

[5] ASSESSING QUALITY OF LIFE IN CANCER-PATIENTS [J].

MAGUIRE, P ;

SELBY, P .

BRITISH JOURNAL OF CANCER, 1989, 60 (03) :437-440

[6] ECONOMIC-EVALUATION AND QUALITY-OF-LIFE ASSESSMENTS IN CANCER CLINICAL-TRIALS - THE CHART TRIAL [J].

MORRIS, J ;

GODDARD, M .

EUROPEAN JOURNAL OF CANCER, 1993, 29A (05) :766-770

[7] MEASURING THE QUALITY OF LIFE OF CANCER-PATIENTS - THE FUNCTIONAL LIVING INDEX, CANCER - DEVELOPMENT AND VALIDATION [J].

SCHIPPER, H ;

CLINCH, J ;

MCMURRAY, A ;

LEVITT, M .

JOURNAL OF CLINICAL ONCOLOGY, 1984, 2 (05) :472-483

[8]

Ware JE, 1993, SF 36 HLTH SURVEY MA

[9] THE HOSPITAL ANXIETY AND DEPRESSION SCALE [J].

ZIGMOND, AS ;

SNAITH, RP .

ACTA PSYCHIATRICA SCANDINAVICA, 1983, 67 (06) :361-370

[10]

Zwinderman A H, 1992, Qual Life Res, V1, P219, DOI 10.1007/BF00635621

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