EFFECTS OF SUSTAINED-RELEASE AND STANDARD PREPARATIONS OF METHYLPHENIDATE ON ATTENTION-DEFICIT DISORDER

被引：62

作者：

FITZPATRICK, PA ^{[1
]}

KLORMAN, R ^{[1
]}

BRUMAGHIM, JT ^{[1
]}

BORGSTEDT, AD ^{[1
]}

机构：

[1] UNIV ROCHESTER, DEPT PSYCHOL, RIVER CAMPUS, ROCHESTER, NY 14627 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1992年 / 31卷 / 02期

关键词：

ATTENTION-DEFICIT HYPERACTIVITY DISORDER; STIMULANTS; METHYLPHENIDATE; SUSTAINED-RELEASE METHYLPHENIDATE; COGNITIVE PERFORMANCE; EVENT-RELATED POTENTIALS;

D O I：

10.1097/00004583-199203000-00008

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Nineteen children with attention deficit disorder (ADD) participated in a double-blind trial consisting of four 2-week phases: sustained-release methylphenidate (MPH); standard MPH; a combination of standard and sustained-release MPH; and placebo. Pharmacological treatments were evaluated by means of parent and teacher ratings and open-ended comments, examiner ratings, and patients' performance and event-related potentials during Continuous Performance and Paired-Associate Learning Tests. Results revealed that the MPH conditions were superior to placebo and comparable to one another. Within the limited time frame of the research, the findings suggest comparable effectiveness for sustained-release and standard preparations of MPH.

引用

页码：226 / 234

页数：9

共 28 条

[1] Barkley R. A, 1981, HYPERACTIVE CHILDREN
[2] Carroll J.B., 1971, AM HERITAGE WORD FRE
[3] COOK EW, 1981, PSYCHOPHYSIOLOGY, V18, P489
[4] DONCHIN E, 1986, PSYCHOPHYSIOLOGY SYS, P702
[5] DOSAGE EFFECTS AND INDIVIDUAL RESPONSIVITY TO METHYLPHENIDATE IN ATTENTION DEFICIT DISORDER
DOUGLAS, VI
BARR, RG
AMIN, K
ONEILL, ME
BRITTON, BG
[J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES, 1988, 29 (04): : 453 - 475
[6] Douglas VI, 1983, DEV NEUROPSYCHIATRY, P280
[7] EFFECTS OF PERCEPTUAL AND COGNITIVE DIFFICULTY ON P3 AND RT IN YOUNG AND OLD ADULTS
FORD, JM
PFEFFERBAUM, A
TINKLENBERG, JR
KOPELL, BS
[J]. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1982, 54 (03): : 311 - 321
[8] FRIEDMAN D, 1978, MULTIDISCIPLINARY PE, P309
[9] GITTELMAN R, 1986, PSYCHOPATHOLOGICAL D, P455
[10] A NEW METHOD FOR OFF-LINE REMOVAL OF OCULAR ARTIFACT
GRATTON, G
COLES, MGH
DONCHIN, E
[J]. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1983, 55 (04): : 468 - 484

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