CUSHINGS-DISEASE DUE TO FEMALE GONADOTROPH ADENOMA OF THE PITUITARY

被引：20

作者：

IKEDA, H ^{[1
]}

YOSHIMOTO, T ^{[1
]}

KOVACS, K ^{[1
]}

HORVATH, E ^{[1
]}

机构：

[1] UNIV TORONTO, ST MICHAELS HOSP, DEPT PATHOL, TORONTO, ON M5B 1W8, CANADA

来源：

CLINICAL ENDOCRINOLOGY | 1995年 / 43卷 / 03期

关键词：

D O I：

10.1111/j.1365-2265.1995.tb02047.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 39-year-old woman presented with amenorrhoea, hyperprolactinaemia and sellar mass. Bromocriptine normalized PRL levels but failed to suppress tumour growth. Subsequently, she developed clinical signs and elevated blood cortisol levels consistent with a diagnosis of Cushing's disease. A pituitary tumour was removed which was immunoreactive for ACTH. Electron microscopic examination, however, revealed a female gonadotroph adenoma indicating that adenoma cells regarded as gonadotrophs by ultrastructural analysis may occasionally secrete ACTH and cause Cushing's disease.

引用

页码：383 / 386

页数：4

共 13 条

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