SUBSTITUENT EFFECTS ON THE H-1 NMR-SPECTRA OF SUBSTITUTED BENZAMIDES AND N-ALKYLBENZAMIDES

The proton chemical shifts (δNH and δCH) of 60 substituted benzamides and N-alkylbenzamides and δCH of seven substituted N, N-dialkylbenzamides have been reported and compared with substituent effects. The chemical shifts (δNH, and δCHof H 3, 5) of N-alkylbenzamides correlate well with Hammett σ values. The chemical shift δ, also correlates well with the Taft substituent constant Es. All other chemical shifts are independent of substituent effects. © 1979, CSIRO. All rights reserved.