The objective of this document is to set the scene with respect to the risk assessment, under Regulation (EC) No 1829/2003 and Directive 2001/18/EC, of Genetically Modified (GM) plants containing stacked transformation events. For the purpose of this document "stacked" events are defined as those combined by conventional breeding1. This document will be used by the EFSA Scientific Panel on Genetically Modified Organisms (GMO Panel) when reviewing and updating its current Guidance Document for risk assessment of genetically modified plants and derived food and feed.