AMPHOTERICIN-B FOLLOWED BY ITRACONAZOLE IN THE TREATMENT OF DISSEMINATED FUNGAL-INFECTIONS IN NEUTROPENIC PATIENTS

被引：10

作者：

NUCCI, M

PULCHERI, W

BACHA, PC

SPECTOR, N

CAIUBY, MJ

COSTA, RO

DEOLIVEIRA, HP

机构：

[1] FED UNIV RIO DE JANEIRO,UNIV HOSP,CLIN PATOL SERV,BR-21945 RIO JANEIRO,BRAZIL

[2] STATE UNIV RIO DE JANEIRO,RIO JANEIRO,BRAZIL

来源：

MYCOSES | 1994年 / 37卷 / 11-12期

关键词：

ASPERGILLOSIS; FUSARIUM-MYCOSIS; CANDIDOSIS; NEUTROPENIA; DISSEMINATION; ANTIMYCOTIC CHEMOTHERAPY; AMPHOTERICIN B; ITRACONAZOLE;

D O I：

10.1111/j.1439-0507.1994.tb00395.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The role of the new triazoles in the treatment of disseminated fungal infections in neutropenic patients is at present under scrutiny. Six neutropenic patients with disseminated fungal infections were treated with amphotericin B during neutropenia and itraconazole after bone marrow recovery. There were three pulmonary aspergillomas, one Aspergillus fumigatus sinusitis, one Fusarium-mycosis and one disseminated candidosis. Four patients were cured of the infection. This approach seems to be safe and effective in the treatment of disseminated fungal infections in neutropenic patients, with the advantages of low side-effects and the possibility of early discharge from hospital.

引用

页码：433 / 437

页数：5

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