ABNORMAL GLYCOSYLATION OF MOTOR-NEURONS WITH N-ACETYL-D-GALACTOSAMINE IN A CASE OF SUBACUTE MOTOR NEURONOPATHY ASSOCIATED WITH LYMPHOMA

被引：12

作者：

NAGAO, M ^{[1
]}

NAKAMURA, M ^{[1
]}

OKA, N ^{[1
]}

AKIGUCHI, I ^{[1
]}

KIMURA, J ^{[1
]}

机构：

[1] TOKYO METROPOLITAN NEUROL HOSP,DEPT NEUROL,TOKYO 183,JAPAN

来源：

JOURNAL OF NEUROLOGY | 1994年 / 241卷 / 06期

关键词：

SUBACUTE MOTOR NEURONOPATHY; MOTOR NEURON; ABNORMAL GLYCOSYLATION; N-ACETYL-D-GALACTOSAMINE; LECTIN;

D O I：

10.1007/BF02033353

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Lectins, glycine max (SBA) and Vicia villosa (VVA), which identify terminal N-acetyl-D-galactosamine (GalNAc), stained the motor neurons of a patient with subacute motor neuronopathy associated with neoplastic angioendotheliosis. In normal controls and in patients with other neurological disorders including amyotrophic lateral sclerosis, neither lectin stained motor neurons. Abnormal glycosylation of motor neurons with terminal galNAc may be associated with the pathogenesis of subacute motor neuronopathy in this patient.

引用

页码：372 / 375

页数：4

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