PRELIMINARY CRYSTAL-STRUCTURE ANALYSIS OF AN FAB SPECIFIC FOR A SALMONELLA O-POLYSACCHARIDE ANTIGEN

被引：12

作者：

ROSE, DR ^{[1
]}

CYGLER, M ^{[1
]}

TO, RJ ^{[1
]}

PRZYBYLSKA, M ^{[1
]}

SINNOTT, B ^{[1
]}

BUNDLE, DR ^{[1
]}

机构：

[1] NATL RES COUNCIL CANADA,BIOTECHNOL RES INST,MONTREAL H4P 2R2,QUEBEC,CANADA

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1990年 / 215卷 / 04期

关键词：

D O I：

10.1016/S0022-2836(05)80161-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Fab from an IgG1, λ murine monoclonal antibody with specificity for the O-polysaccharide antigen of Salmonella typhimurium has been crystallized in the absence and presence of hapten. The conditions for crystal growth were vapor diffusion equilibration with 16 to 23% polyethylene glycol 8000 solutions. Data have been collected from crystals of the complex in space group P212121, a = 60·6 Å, b = 111·3 Å, c = 61·1 Å, and refinement of a molecular replacement solution is underway. © 1990 Academic Press Limited.

引用

页码：489 / 492

页数：4

共 15 条

[1] PROTEIN DATA BANK - COMPUTER-BASED ARCHIVAL FILE FOR MACROMOLECULAR STRUCTURES
BERNSTEIN, FC
KOETZLE, TF
WILLIAMS, GJB
MEYER, EF
BRICE, MD
RODGERS, JR
KENNARD, O
SHIMANOUCHI, T
TASUMI, M
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1977, 112 (03) : 535 - 542
[2] THE CONFORMATION OF SALMONELLA O-ANTIGENIC OLIGOSACCHARIDES OF SEROGROUP-A, SEROGROUP-B, AND SEROGROUP-D1 INFERRED FROM H-1-NUCLEAR AND C-13-NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY
BOCK, K
MELDAL, M
BUNDLE, DR
IVERSEN, T
PINTO, BM
GAREGG, PJ
KVANSTROM, I
NORBERG, T
LINDBERG, AA
SVENSON, SB
[J]. CARBOHYDRATE RESEARCH, 1984, 130 (JUL) : 35 - 53
[3] THE CONFORMATION OF SALMONELLA O-ANTIGENIC POLYSACCHARIDE CHAINS OF SEROGROUP-A, SEROGROUP-B, AND SEROGROUP-D1 PREDICTED BY SEMI-EMPIRICAL, HARD-SPHERE (HSEA) CALCULATIONS
BOCK, K
MELDAL, M
BUNDLE, DR
IVERSEN, T
GAREGG, PJ
NORBERG, T
LINDBERG, AA
SVENSON, SB
[J]. CARBOHYDRATE RESEARCH, 1984, 130 (JUL) : 23 - 34
[4] A MEMORY-EFFICIENT FAST FOURIER TRANSFORMATION ALGORITHM FOR CRYSTALLOGRAPHIC REFINEMENT ON SUPERCOMPUTERS
BRUNGER, AT
[J]. ACTA CRYSTALLOGRAPHICA SECTION A, 1989, 45 : 42 - 50
[5] A FULL-SYMMETRY TRANSLATION FUNCTION BASED ON ELECTRON-DENSITY
CYGLER, M
DESROCHERS, M
[J]. ACTA CRYSTALLOGRAPHICA SECTION A, 1989, 45 : 563 - 572
[6] APPLICATION OF THE MOLECULAR REPLACEMENT METHOD TO MULTIDOMAIN PROTEINS .1. DETERMINATION OF THE ORIENTATION OF AN IMMUNOGLOBULIN FAB FRAGMENT
CYGLER, M
ANDERSON, WF
[J]. ACTA CRYSTALLOGRAPHICA SECTION A, 1988, 44 : 38 - 45
[7] EXPERIENCES WITH A NEW TRANSLATION-FUNCTION PROGRAM
FUJINAGA, M
READ, RJ
[J]. JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1987, 20 : 517 - 521
[8] Kauffmann F., 1966, BACTERIOLOGY ENTEROB
[9] LINDBERG AA, 1983, ACS SYM SER, V231, P83
[10] LUDERITZ O, 1966, BACTERIOL REV, V30, P192

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