MULTICOMPONENT ANALYSIS IN SOLUTION USING PIEZOELECTRIC QUARTZ SENSORS .2. DETERMINATION OF ASPIRIN AND SALICYLIC-ACID IN AQUEOUS-SOLUTIONS

被引:9
作者
WEI, WZ
NIE, LH
YAO, SZ
机构
[1] Department of Chemistry and Chemical Engineering, Hunan University, Changsha
关键词
CONDUCTOMETRY; ASPIRIN; PHARMACEUTICALS; PIEZOELECTRIC SENSOR; QUARTZ CRYSTAL; SALICYLIC ACID;
D O I
10.1016/0003-2670(92)85428-9
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Based on the linear relationship between the conductivity of an aqueous solution and the piezoelectric quartz sensor frequency, it was derived that under certain experimental conditions the frequency shift should show a linear dependence on concentration for common acids and aspirin. This verified experimentally. A calibration model for the simultaneous determination of aspirin (ASA) and salicylic acid (SA) was established. The usefulness of the technique was evaluated by the analysis of mixtures of known composition using a P-matrix calibration method. The average relative errors were 0.81% for ASA and 1.63% for SA.
引用
收藏
页码:77 / 83
页数:7
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