Microbeam radiation therapy of the intracerebral 9L gliosarcoma in rats, an experimental surrogate for human malignant gliomas, using mainly 30-130 keV wiggler-generated x rays, extended the residual lifespans of some rats ten or more times over those of untreated, similar gliosarcoma-bearing rats. The rats were exposed 300 or 600 times to an upright, 25-μm-wide, 4-mm-high x-ray beam. A multislit collimator has been designed to shorten the time required for the therapy. © 1995 American Institute of Physics.