ENVIRONMENTAL EXPOSURES IN ELDERLY CANADIANS WITH PARKINSONS-DISEASE

被引：30

作者：

CHATURVEDI, S

OSTBYE, T

STOESSL, AJ

MERSKEY, H

HACHINSKI, V

机构：

[1] UNIV WESTERN ONTARIO,FAC MED,DEPT EPIDEMIOL & BIOSTAT,LONDON,ON N6A 5C1,CANADA

[2] UNIV WESTERN ONTARIO,FAC MED,DEPT CLIN NEUROL SCI,LONDON,ON N6A 5C1,CANADA

[3] UNIV WESTERN ONTARIO,FAC MED,DEPT PSYCHIAT,LONDON,ON N6A 5C1,CANADA

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1995年 / 22卷 / 03期

关键词：

D O I：

10.1017/S0317167100039901

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Etiologic hypotheses for Parkinson's disease have implicated environmental factors, genetic factors, or a combination of the two. Methods: Data from a survey of elderly Canadians (n = 10,263) with regard to their history of Parkinson's disease and previous environmental exposures were analyzed. Exposure to various environmental factors was compared between 87 patients with Parkinson's disease and 2070 elderly controls without Parkinson's disease. Results: Exposure to plastic resins (OR (odd ratio) = 8.79), epoxy resins (OR = 6.94), glues (OR = 4.26), paints (OR = 3.84), and petroleum (OR = 2.30) products was significantly (p < 0.05) associated with Parkinson's disease. Conclusion: These substances deserve further exploration with respect to the possible development of parkinsonism.

引用

页码：232 / 234

页数：3

共 10 条

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