HIGH-PRESSURE, REVERSE-PHASE PARTITION CHROMATOGRAPHY SEPARATION OF DIETHYLSTILBESTROL METABOLITES AND ANALOGS

被引：22

作者：

GOTTSCHLICH, R

METZLER, M

机构：

[1] Institute of Toxicology, University of Würzburg. Versbacher, D-8700 Würzburg

来源：

ANALYTICAL BIOCHEMISTRY | 1979年 / 92卷 / 01期

关键词：

D O I：

10.1016/0003-2697(79)90645-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Various conjugated and oxidative metabolites of diethylstilbestrol were effectively separated by high-pressure, reverse-phase liquid chromatography on C8- and C18-hydrocarbon phases with water-methanol gradients. The transplacental toxicity of diethylstilbestrol has stimulated interest in the metabolic fate of this synthetic estrogen.

引用

页码：199 / 202

页数：4

共 10 条

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