ACUTE-RENAL-FAILURE FOLLOWING HYPOKALEMIC RHABDOMYOLYSIS DUE TO CHRONIC GLYCYRRHIZIC ACID ADMINISTRATION

被引：21

作者：

CHUBACHI, A

WAKUI, H

ASAKURA, K

NISHIMURA, S

NAKAMOTO, Y

MIURA, AB

机构：

[1] Department of Internal Medicine, Yuri Kumiai General Hospital, Honjo

[2] Third Department of Internal Medicine, Akita University School of Medicine, Akita

来源：

INTERNAL MEDICINE | 1992年 / 31卷 / 05期

关键词：

GLYCYRRHIZIN; HYPOKALEMIA; MYOGLOBINURIC RENAL FAILURE;

D O I：

10.2169/internalmedicine.31.708

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 72-year-old man developed acute renal failure (ARF) following severe hypokalemic rhabdomyolysis. The hypokalemia was due to chronic glycyrrhizin (glycyrrhizic acid) administration. Although glycyrrhizin-induced hypokalemic rhabdomyolysis has been occasionally reported, the association of this type of rhabdomyolysis with ARF has not been described. In the present case, there was a sensitivity to glycyrrhizin the preceding renal insufficiency, and dehydration which was thought to have contributed to ARF. It should be recognized that elderly patients with such predisposing factors may be susceptible to a rapid deterioration of renal function after glycyrrhizin-induced hypokalemic rhabdomyolysis.

引用

页码：708 / 711

页数：4

共 19 条

[1]

Conn J.W., Rovner D.R., Cohen E.L., Licorice-induced pseudoaldosteronism, hypertension, hypokalemia, aldosteropenia and suppressed plasma renin activity, J Am Med Assoc, 205, (1968)

[2]

Montero F., Exogenous mineralocorticoid-like disorders, Clin Endocrinol Metab, 10, (1981)

[3]

Heidemann H.T., Kreuzfelder E., Hypokalemic rhabdomyolysis with myoglobinuria due to the licorice ingestion and diuretic treatment, Klin Wochenschr, 61, (1983)

[4]

Nielsen I., Pederson R.S., Life-threatening hypokalemia caused by liquorice ingestion, Lancet, 2, (1984)

[5]

Ashar K.N., Abduo T.J., Menon N.K., Severe hypokalemic rhabdomyolysis due to ingestion of liquorice during Ramadan, Aust NZ J Med, 19, (1989)

[6]

Kuriyama Y., Takano T., Okada F., Nukada T., Hypersensitivity to glycyrrhizin

[7]

A case report, Med J Osaka Univ, 26, (1975)

[8]

Sugimoto K., Shionoiri H., Inoue K., Kaneko Y., A case report of hypokalemic myopathy due to ingestion of large doses of “Jintan”, Nihon Naika Gakkai Zasshi, 73, (1984)

[9]

Okada K., Kobayashi S., Tsunematsu T., A case of Sjögren's syndrome associated with hypokalemic myopathy due to glycyrrhizin, Nihon Naika Gakkai Zasshi, 76, (1987)

[10]

Fujimori Y., Okamoto S., Tsujii T., Et al., Three cases of pseudoaldosteronism due to methanol extracts of licorice (FM-100), J Jpn Soc Int Med, 76, (1987)

← 1 2 →