CLINICAL MODULATION OF DOXORUBICIN RESISTANCE BY THE CALMODULIN-INHIBITOR, TRIFLUOPERAZINE - A PHASE-I/II TRIAL

被引：144

作者：

MILLER, RL

BUKOWSKI, RM

BUDD, GT

PURVIS, J

WEICK, JK

SHEPARD, K

MIDHA, KK

GANAPATHI, R

机构：

[1] CLEVELAND CLIN EDUC FDN,DEPT HEMATOL ONCOL,9500 EUCLID AVE,CLEVELAND,OH 44106

[2] CLEVELAND CLIN EDUC FDN,DEPT CANC & IMMUNOL,CLEVELAND,OH 44106

[3] NCI,BRMP,FREDERICK,MD 21701

[4] UNIV SASKATCHEWAN,COLL PHARM,SASKATOON S7N 0W0,SASKATCHEWAN,CANADA

[5] UNIV SASKATCHEWAN,COLL MED,SASKATOON S7N 0W0,SASKATCHEWAN,CANADA

[6] BURROUGHS WELLCOME CO,RES TRIANGLE PK,NC 27709

来源：

JOURNAL OF CLINICAL ONCOLOGY | 1988年 / 6卷 / 05期

关键词：

D O I：

10.1200/JCO.1988.6.5.880

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：880 / 888

页数：9

共 31 条

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[9] DIFFERENTIAL EFFECT OF THE CALMODULIN INHIBITOR TRIFLUOPERAZINE IN MODULATING CELLULAR ACCUMULATION, RETENTION AND CYTO-TOXICITY OF DOXORUBICIN IN PROGRESSIVELY DOXORUBICIN-RESISTANT L1210 MOUSE LEUKEMIA-CELLS - LACK OF CORRELATION BETWEEN CELLULAR DOXORUBICIN LEVELS AND EXPRESSION OF RESISTANCE [J].

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