METALATION OF AROMATIC TERTIARY DIAMINES WITH NORMAL-BUTYLLITHIUM

被引：6

作者：

FRIEDMANN, G

LINDER, P

BRINI, M

CHEMINAT, A

机构：

[1] Laboratoire de Synthèse Organique, Institut de Chimie, 1, rue Blaise Pascal, Strasbourg Cedex

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 02期

关键词：

D O I：

10.1021/jo01316a017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report the results obtained by direct metalation of aromatic tertiary diamines with n-BuLi. The reaction done in a nonpolar solvent, such as hexane, at elevated temperature (60°C) shows the formation of both a mono-lithiated and a dilithiated compound, the site of lithiation being the ortho position of the benzene ring as evidenced by 1H NMR data. The metalation was followed by gas chromatography by measuring the butane evolved during the reaction. Copyright © 1979, American Chemical Society. All rights reserved.

引用

页码：237 / 239

页数：3

共 9 条

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