NONINVASIVE PREDICTION OF SAR DISTRIBUTIONS WITH AN ELECTROOPTICAL E-FIELD SENSOR

被引:17
作者
WUST, P
MEIER, T
SEEBASS, M
FAHLING, H
PETERMANN, K
FELIX, R
机构
[1] TECH UNIV BERLIN,FACHBEREICH ELEKTROTECH,D-10587 BERLIN,GERMANY
[2] KONRAD ZUSE ZENTRUM,D-10711 BERLIN,GERMANY
关键词
RADIOFREQUENCY; HYPERTHERMIA; E FIELD SENSOR;
D O I
10.3109/02656739509022464
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
An integrated electro-optical (eo) E field sensor is developed on the basis of a Ti:LiNbO3 Mach-Zehnder interferometer. A measuring device based on the lock-in principle is introduced to register the E field in phase and amplitude using this E field probe. Segmented electrodes are used to minimize influences from the dielectric surroundings on the base point capacitance of the receiving dipole. The operating point is stabilized against drift phenomena resulting from optical damage and pyroelectric effect. Sensitivity, dynamic range, harmonic distortions and mechanical properties of a prototype of this electro-optical E field sensor are evaluated. A phantom setup in the SIGMA-60 applicator was developed to test this electro-optical sensor for hyperthermia applications. Power deposition patterns of various standard adjustments of the SIGMA ring are visualized in an elliptical lamp phantom. Simultaneously, E field in phase and amplitude is determined on a closed curve in 10 degrees steps around the phantom in a substitute bolus. The numbers are stored and utilized as boundary conditions in a two-dimensional finite elements code which calculates the SAR distribution on an appropriate triangular grid inside the closed curve. An excellent qualitative agreement is obtained between visualized and calculated SAR patterns. This novel measurement method is therefore suitable for noninvasive monitoring of SAR patterns during clinical application of regional radiofrequency hyperthermia.
引用
收藏
页码:295 / 310
页数:16
相关论文
共 35 条
[1]  
ALFERNESS RC, 1990, GUIDED WAVE OPTOELEC, P145
[2]   ELECTRIC-FIELD PROBES - A REVIEW [J].
BASSEN, HI ;
SMITH, GS .
IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, 1983, 31 (05) :710-718
[3]  
BENYOSEF R, 1992, INT J HYPERTHER, V8, P175
[4]  
Bolomey J. C., 1990, METHODS HYPERTHERMIA, P35
[6]  
BURNS WK, 1986, APPL PHYS LETT, V48, P1036
[7]  
DOHLUS M, 1992, THESIS TH DARMSTADT
[8]   THERMORADIOTHERAPY IN LOCALLY ADVANCED DEEP SEATED TUMORS - THERMAL PARAMETERS AND TREATMENT RESULTS [J].
FELDMANN, HJ ;
MOLLS, M ;
HEINEMANN, HG ;
ROMANOWSKI, R ;
STUSCHKE, M ;
SACK, H .
RADIOTHERAPY AND ONCOLOGY, 1993, 26 (01) :38-44
[9]   OPTICAL-DAMAGE RESISTANCE OF LITHIUM-NIOBATE WAVEGUIDES [J].
HOLMAN, RL ;
CRESSMAN, PJ .
OPTICAL ENGINEERING, 1982, 21 (06) :1025-1032
[10]   IMPROVEMENT OF LOCAL-CONTROL BY REGIONAL HYPERTHERMIA COMBINED WITH SYSTEMIC CHEMOTHERAPY (IFOSFAMIDE PLUS ETOPOSIDE) IN ADVANCED SARCOMAS - UPDATED REPORT ON 65 PATIENTS [J].
ISSELS, RD ;
MITTERMULLER, J ;
GERL, A ;
SIMON, W ;
ORTMAIER, A ;
DENZLINGER, C ;
SAUER, H ;
WILMANNS, W .
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1991, 117 :S141-S147