HEREDITARY DNA ALTERATIONS

被引：8

作者：

FREESE, E

机构：

[1] Laboratory of Molecular Biology, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare, Bethesda, Maryland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1969年 / 8卷 / 01期

关键词：

Chromosomes; Hereditary DNA alterations; Mutations; Nucleic acids;

D O I：

10.1002/anie.196900121

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mutations and recombinations are hereditary alterations of DNA, which is found mainly in the chromosomes of cells. They can occur spontaneously and they can be induced by high energy radiation or by chemicals. This article considers the developments following the discovery of the DNA structure that have led to a molecular explanation of point mutations, of large chromosome alterations, and of recombination. In conclusion, consequences for human society are drawn from the knowledge gained. Copyright © 1969 by Verlag Chemie, GmbH, Germany

引用

页码：12 / &

共 90 条

[1] COMPARISON OF THE CHANGES PRODUCED BY IONIZING RADIATIONS AND BY THE ALKYLATING AGENTS - EVIDENCE FOR A SIMILAR MECHANISM AT THE MOLECULAR LEVEL [J].