THE IMPACT OF EMBRYO QUALITY ON PREGNANCY OUTCOME IN ELDERLY WOMEN UNDERGOING INVITRO FERTILIZATION EMBRYO TRANSFER (IVF-ET)

被引：22

作者：

FELDBERG, D ^{[1
]}

FARHI, J ^{[1
]}

DICKER, D ^{[1
]}

ASHKENAZI, J ^{[1
]}

SHELEF, M ^{[1
]}

GOLDMAN, JA ^{[1
]}

机构：

[1] HASHARON HOSP,GOLDA MEIR MED CTR,DEPT OBSTET GYNECOL,SHERMAN INST FERTIL,IL-49372 PETAH TIQWA,ISRAEL

来源：

JOURNAL OF IN VITRO FERTILIZATION AND EMBRYO TRANSFER | 1990年 / 7卷 / 05期

关键词：

elderly women; embryo quality; in vitro fertilization; pregnancy outcome;

D O I：

10.1007/BF01129530

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Most IVF-ET units limit the procedure to women below age 38. Nevertheless, demands for infertility treatment, including IVF therapy, are more frequent nowadays. We compared 46 cycles for ovulation induction for IVF in 46 women aged 40 or more (Group I) to 51 induced cycles for this procedure in younger women of mean age 30.2 years (Group II). Cancellation rates due to early luteinization or ovulation were significantly higher in group I than in group II (28.2 and 17.6%, respectively) (P<0.001). Also, significantly higher abortion rates were observed in older women (62.5%), in comparison to the younger control group, (25%), (P<0.001). It is suggested that the high abortion rate considered to be due to genetic factors in older women, may possibly also be due to the aging uterine environment. Furthermore, while embryos with fragmentations may often produce clinical pregnancies in the young, the aging uterus in the elderly woman does not encourage the development of clinical pregnancies in such embryos. Consequently the higher abortion rate in the elderly woman. © 1990 Plenum Publishing Corporation.

引用

页码：257 / 261

页数：5

共 19 条

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